Publicaciones 2017

Stortz M, Angiolini J, Mocksos E, Wolosiuk A, Pecci A and Levi V. Mapping the dynamical organization of the cell nucleus through fluorescence correlation spectroscopy. Methods 2017 doi: 10.1016/j.ymeth.2017.12.008.

Alvarez LD, Presman DM and Pecci A. Molecular dynamics simulations of the glucocorticoid receptor DNA-binding domain suggest a role of the lever-arm mobility in transcriptional output. PlosOne 2017.12(12):e0189588. DOI: 10.1371/journal.pone.0189588.

Stortz M, Presman DM, Bruno L, Annibale P, Dansey MV, Burton G, Gratton E, Pecci* A and  Levi* V (*autorascorrespondientes) Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape. Scientific Reports, 2017. 7(1):6219-6231 DOI:  10.1038/s41598-017-06676-0

Publicaciones 2016

Rodriguez CR; Alvarez LD; Dansey MV; Paolo LS; Veleiro AS; Pecci A and Burton G. Fluorinated oxysterol analogues: synthesis, molecular modelling and LXRß activity. J of Steroid Biochemistry and Mol Biology. 2017 165(Pt B):268-276. DOI: 10.1016/j.jsbmb.2016.07.001

-Astort F; Repetto EM; Rocha-Viegas L; Mercau ME; Sanchez Puch S; Finkielstein CV; Pecci A and Cymeryng CB. Role of CREB on Heme Oxygenase-1 Induction in Adrenal Cells.Involvement of the PI3K Pathway.J of Molecular Endocrinology. 2016 Aug;57(2):113-24. DOI: 10.1530/JME-16-0005.

del Fueyo, MC, Dansey, MV, Paolo, LS, Pecci, A, Veleiro, AS and Burton, G. C(16)-C(22) Oxygen-bridged analogues of ceDAF-12 and LXR ligands: Synthesis and biological activity. Steroids.2016 112:109-14. DOI: 10.1016/j.steroids.2016.05.009

Pecci A, Alvarez LD, Presman DM, Burton G. 21-hydroxy-6,19-epoxyprogesterone: a Promising Therapeutic Agent and a Molecular Tool for Deciphering Glucocorticoid Action. Mini Rev Med Chem. 2016 Jan 17. DOI: 10.2174/1389557517666171002155430

Publicaciones 2015

-Grinman DY, Romorini L, Presman DM, Rocha-Viegas L, Coso OA, Davio C and Pecci A. Role of 3′-5′-cyclic Adenosine Monophosphate on the Epidermal Growth Factor Dependent Survival in Mammary Epithelial Cells. Molecular and Cellular Endocrinology. 2016 5;419:259-67. DOI: 10.1016/j.mce.2015.10.026.

-Alvarez LD, Dansey MV, Grinman DG; Navalesi D; Samaja GA, del Fueyo MC; Bastiaensen N; Houtman R; Estrín DA; Veleiro AS; Pecci A* and Burton G* (*autores correspondientes). Destabilization of the torsioned conformation of a ligand side chain inverts the LXRß activity. BBA – Molecular and Cell Biology of Lipids. 2015 1851(12):1577-86. DOI: 10.1016/j.bbalip.2015.09.007

-Chiappe VB, Gómez MV, Rodríguez C, Fresolone M, Pecci A, Romanelli HJ. Subgingivally Applied Minocycline Microgranules in Subjects with Chronic Periodontitis.A Randomized Clinical and Microbiological Trial.Acta Odontol. Latinoam. 2015 Vol. 28 Nº 2:122-131. DOI: 10.1590/S1852-48342015000200005

-Nemirovsky SI, Córdoba M, Zaiat JJ, Completa SP, Vega PA, González-Morón D, Medina NM, Fabbro M, Romero S, Brun B, Revale S, Ogara MF, Pecci A, Marti M, Vazquez M, Turjanski A, Kauffman MA. Whole Genome Sequencing Reveals a De Novo SHANK3 Mutation in Familial Autism Spectrum Disorder. PLoS One. 2015 10(2):e0116358. DOI: 10.1371/journal.pone.0116358

-Dansey MV, Alvarez LD, Samaja G, Escudero DS, Veleiro AS, Pecci A, Castro OA, Burton G. Synthetic DAF-12 modulators with potential use in controlling nematodes life cycle. Biochemical J. 2015. 465(1):175-184. DOI: 0.1042/BJ20140833.

noticia

Una bomba de tiempo en el panal

Un estudio realizado en abejas melíferas jóvenes, aquellas que aún no salen a recolectar néctar, mostró que la exposición crónica a trazas de glifosato e insecticidas en el alimento afecta la sensibilidad gustativa y la memoria. Esos efectos nocivos, que ya habían sido observados en abejas adultas recolectoras, pueden poner en riesgo la supervivencia de las colmenas.

https://nexciencia.exactas.uba.ar/una-bomba-de-tiempo-en-el-panal